Chronic intestinal pseudo obstruction: a rare first manifestation of systemic lupus erythematosus

翻译者：王小静 校对者：郭乾育 审核者：张莉芸

Chronic intestinal pseudo obstruction (CIPO) is a rare clinical syndrome of ineffective intestinal motility characterised by clinical and radiological evidence of intestinal obstruction with no identifiable mechanical lesion. CIPO can either be idiopathic or secondary to a systemic disease, like systemic lupus erythematosus (SLE). Fewer than 30 cases of CIPO secondary to SLE have been reported so far. Here we describe a case of SLE with the initial presentation of CIPO. In SLE-related CIPO, treatment includes a combination of high-dose intravenous corticosteroids, immunosuppressants and supportive care. With awareness of this condition, unnecessary surgical intervention and repeated invasive procedures could be avoided. Early initiation of treatment would avoid complications and bring about resolution of symptoms.

慢性假性肠梗阻（CIPO）是一种罕见的临床综合征，临床和影像学有肠梗阻的表现，但无机械性肠梗阻的证据。CIPO可以是特发的，也可以继发于其它系统性疾病，如SLE。目前为止，已经报道了近30例的继发于SLE的CIPO。本文讨论一例以CIPO为首发症状的SLE。与SLE相关的CIPO，治疗上包括静脉用大剂量糖皮质激素,免疫抑制剂及支持治疗。意识到这一点，可以避免不必要的外科介入和重复性侵入操作。早期治疗可以避免并发症，并能够改善症状。