To explore the possible abnormal resting-state activity

in patients with obsessive-compulsive disorder (OCD),

the regional homogeneity (ReHo) of 22 pairs of patients

and well-matched healthy controls was calculated.

Compared with controls, the patients showed higher

ReHo in the left anterior cingulate cortex, but lower

ReHo in the left inferior temporal gyrus. These findings

supported the abnormal resting-state brain activity in

drug-naı¨ve OCD patients. No significant correlations

between ReHo value and four clinical characteristics

were found, suggesting that abnormal ReHo might be

trait-related in OCD.